A Public Policy Quarterly of The Ramazzini Institute

Volume Two, Number Three                               Summer 2001
 


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William Jamieson Nicholson
Pioneer of Science, Sensitive Human, Touchstone for Integrity

    
April 9th, while jogging near his home in Fair Lawn, New Jersey, William J. Nicholson, PhD, suffered heart failure. A life-long athlete, he was 70 years old. An officer and a founding member of the Board of The Ramazzini Institute, Dr. Nicholson was Professor Emeritus in Community and Preventive Medicine at Mt. Sinai School of Medicine, New York.
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In This Issue

Geoffrey Lomax
IOM Roundtable on Cancer and the Environment:
Gene-Environment Interactions

    
An important report on genes and their environments from the Institute of Medicine, of the National Academy of Sciences in Washington, DC May 16-17. ABC-TV’s Sam Donaldson weighs in for more agreement among scientists. Former Illinois Congressman John Porter calls on scientists to “engage” their representatives against relaxing environmental standards during the energy crunch, and to take the “squeeze” out of the environmental health research budget. Karolinska’s Kari Hemminki casts more light on the relative contributions of genetic and environmental factors in causing cancer through an unique study of twins in Scandinavia.
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Mary Davidson
Legislation Needed To Stop Genetic Discrimination

     The Executive Director of an international coalition outlines four policy principles to guide an end to genetic discrimination.

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New Name, Expanded Horizon
The “Project” Becomes A Consortium!

     The Amarillo Health Project gets a new name, The Amarillo Health Consortium, and in the process expands it’s horizons and mission as a community-based agency focused on occupational and environmental health. First task: cancer detection.
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Moral Questions
Dear Unsigned: Hayek Would Not Regulate Stem Cell Research With “Market Strategies”

    A letter-to-the-editor from a reader used our archives, accessed our October 2000 issue, found an article relevant to the current international debate on the use of stem cells in biomedical research, and asked a good moral question on ethical issues raised by dependence on the marketplace. The question leads us to ask another: how really “voluntary” are “volunteer “ research subjects paid a “market” price for their risks in stem cell [or any] research?
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Nancye Buelow
Unique, Urgent Need for Blood Plasma Availability

 
Safe and available blood plasma supplies for patients with alpha-1 antitrypsin deficiency are in danger. Help from the Secretary of Health and Human Services is needed!
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 News In Brief!

 September Update

  • Possible Gene Therapy for Alpha-1. A team of researchers headed by TR Flotte at the University of Florida injected a virus containing the DNA for human alpha-1 antitrypsin in the veins of mice, and achieved levels of the protein that could be therapeutic for a year. Humans who inherit a deficiency of the protein may be predisposed to lung and liver disease, often triggered by environmental factors. The virus is unlike the strain implicated in a death after gene therapy at the University of Pennsylvania in 1999, which led to a temporary halt in human trials. New trials using different viruses have been approved. Contributing Editor Robert Sandhaus, who is Executive Vice President of the Alpha One Foundation, cautioned that “this is uncharted territory and movement forward will need to be done with care.” National Institutes of Health and the Foundation supported the research, The report appears in the September 2001 issue of Gene Therapy. See our archives for additional information on Alpha-1.
  • Heart Repaired By Adult Stem Cells? Cardiologist BE. Strauer and stem cell researcher Peter Wernet used stem cells from a patient’s own body to possibly achieve a reduction of damaged tissue and an improvement in heart performance. The Frankfurter Allgemeine Zeitung [Aug. 24, 2001] reported that the researchers, from Dusseldorf’s Heinrich Heine University, “extracted stem cells from bone marrow in the 46-year-old patient’s pelvis and injected them into his aorta.” The doctors warned that the patient might have recovered on his own without help from the injected cells, making further tests necessary before wide use.
  • Human Genetics, Environment and Communities of Color: Ethical and Social Implications. Conference at Columbia University, Sept. 20, 2001. Speakers: Kenneth Olden, Director of the National Institute for Environmental Health Sciences; Eula Bingham, University of Cincinnati; and Paul Schulte, National Institute of Occupational Safety and Health. Details? www.weact.org
  • Genetics, Policy and Law: A National Forum. Oct. 5, 2001,Washington, DC. Hosts: Genetic Technologies Project of National Conference of State Legislatures, Georgetown University Law Center, and Johns Hopkins School of Hygiene and Public Health. Major address by NHGRI Director Francis Collins. Information? www.ncsl.or/programs/health/genetics/oct-meet.htm

…The Editors


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